Oral Sun Protection: Can You Protect Your Skin from the Sun with a Pill?

We all know the importance of sunscreen in protecting our skin from the sun’s harmful rays. But did you know that sun protection doesn’t only come in the form of a lotion or spray? Oral sun protection—in the form of dietary supplements—is an emerging option that may provide additional support, especially for individuals with sun sensitivities, pigment disorders like melasma or vitiligo, or a history of skin cancer.

While these supplements are not a replacement for sunscreen, they can be a helpful complement. Here’s a breakdown of the most researched options, how they work, and what to consider before adding them to your routine.

Oral Sun Protection Options

Polypodium Leucotomos Extract (PLE)

Common Brands: Heliocare®, Fernblock®

PLE is a natural extract from a tropical fern native to Central America. It has antioxidant and anti inflammatory properties that help protect the skin from UV damage by:

• Neutralizing free radicals

• Supporting skin structure

• Reducing inflammation caused by sun exposure

How to use:

Available over the counter, PLE supplements are typically taken during periods of sun exposure. They may help reduce sunburn severity and UV-related DNA damage but should always be used alongside topical sunscreen for best results.

Niacinamide (Vitamin B3)

Niacinamide is a well-researched form of vitamin B3 that supports skin health by:

• Enhancing DNA repair

• Strengthening the skin barrier

• Supporting the immune system in the skin

Clinical benefits:

Studies have shown that taking 500 mg twice daily of niacinamide may reduce the risk of developing non-melanoma skin cancers like basal cell carcinoma and squamous cell carcinoma in high-risk individuals. While it’s not technically a “sunscreen,” niacinamide offers significant protective effects and is readily available over the counter.

Antioxidant Supplements (Vitamins C & E)

Vitamins C and E are antioxidants that help neutralize oxidative stress caused by UV exposure. When taken regularly, they may:

• Reduce inflammation

• Support collagen and skin repair

• Help prevent signs of photoaging

  
  

These are typically included in multivitamin or skin health formulations and are most effective when used alongside other protective measures.

Bottom Line: Supplements Enhance, Not Replace

Oral sun protection is a promising and growing area in dermatology, but it is not a standalone defense. These supplements should be used in combination with:

• Broad-spectrum sunscreen (SPF 30 or higher)

• Sun-protective clothing and wide-brimmed hats

• Sunglasses with UV protection

• Limiting sun exposure during peak hours (10 a.m. – 4 p.m.)

Talk to Your Dermatologist First

If you’re curious about adding oral sun protection to your skincare regimen—especially if you have a history of sun damage, skin cancer, or photosensitivity—talk to your dermatology provider. We can help you choose the right combination of topical and oral options to keep your skin healthy, radiant, and protected all year long.