Summer Insect Repellent Guide
- Northeast Dermatology
- May 26
- 4 min read

Summertime has arrived! Sunshine is always welcome, but unfortunately they come with some uninvited guests; biting insects. Read on to learn what to look for in products that are actually effective, plus other practical ways to reduce insect exposure this season.
Insect repellent is important not only to avoid itchy bites, but also to help prevent insect borne illness. In Ohio and much of the Midwest, tick-borne diseases such as Lyme Disease and Rocky Mountain Spotted Fever remain concerns. Travelers should also consider protection against mosquito-borne illnesses including Malaria, Dengue Fever, West Nile Virus, and Zika Virus Disease.
Repellents are widely available in sprays, lotions, creams, wipes, sticks, and wearable formulations. The most important factor is choosing an EPA-registered product with a proven active ingredient and using it correctly.
Bottom Line Insect Repellent Recommendations
The below post contains LOTS of information, but the big takeaways are collected here for your convenience!
For most adults and families, the best-supported options remain:
1. Picaridin 20% — excellent protection, fabric-safe, low odor
2. DEET 20–30% — highly effective and widely available
3. Oil of Lemon Eucalyptus (PMD) — strongest plant-based option
For outdoor activities involving ticks (hiking, camping, yard work), combine skin repellent and permethrin-treated clothing. That combination provides the best protection against both mosquitoes and ticks.
Insect Repellent Options
DEET
Average duration: ~4–8 hours depending on concentration and conditions
Recommended concentration: 20%–30% works well for most adults; concentrations
above 50% generally do not provide significantly longer protection
Popular brands: OFF!, Ben's
Effective against: mosquitoes, ticks, biting flies
Highlights:
DEET remains one of the most studied and effective insect repellents available.
Current guidance from the American Academy of Pediatrics supports use in children
older than 2 months when used as directed.
Apply sunscreen first, allow it to dry, then apply insect repellent separately rather than
relying on combination SPF/repellent products.
DEET can damage certain plastics, synthetic fabrics, watch faces, and eyeglass coatings.
Picaridin
Average duration: 8–12 hours at 20% concentration
Popular brands: OFF!, Natrapel, Sawyer
Effective against: mosquitoes, ticks, biting flies
Highlights:
Picaridin has become one of the top-recommended alternatives to DEET because it:
has little odor
feels less greasy
is less irritating to skin
does not damage plastics or fabrics
Studies show protection comparable to moderate concentrations of DEET against
mosquitoes and ticks.
IR3535
Average duration: 2–6 hours depending on concentration
Popular brands: Avon Skin So Soft
Effective against: mosquitoes, ticks
Highlights:
IR3535 is a synthetic amino-acid–based repellent with a favorable safety profile.
Often used in family-friendly formulations.
May still damage some plastics and synthetic materials.
Oil of Lemon Eucalyptus (OLE / PMD)
Average duration: up to 6 hours
Popular brands: OFF! Botanicals, Repel
Effective against: mosquitoes, some tick protection
Highlights:
Oil of Lemon Eucalyptus (specifically PMD-containing products) is one of the few plant-
based repellents recommended by the Centers for Disease Control and Prevention.
Important distinction: “Pure lemon eucalyptus essential oil” is not the same as EPA-registered
OLE/PMD products.
Not recommended for children under 3 years old.
Oil of Citronella
Average duration: ~1–2 hours
Popular brands: Buzz Away
Effective against: mosquitoes
Highlights:
Citronella-based repellents may help briefly, but protection is shorter-lived than DEET or
picaridin.
More frequent reapplication is necessary.
Candles and wearable citronella devices have limited effectiveness outdoors, especially
in wind.
Catnip Oil
Average duration: Variable; evidence remains limited
Effective against: mosquitoes in laboratory settings
Highlights:
Catnip oil has shown promising mosquito repellency in some studies, but there are still
fewer real-world studies and limited commercial availability compared with DEET or picaridin.
Not currently a mainstream CDC-recommended repellent.
2-Undecanone (Wild Tomato Extract)
Average duration: ~4–5 hours
Popular brands: BioUD
Effective against: mosquitoes, ticks
Highlights:
EPA-registered and increasingly recognized as a plant-derived alternative option.
More data has become available since its original introduction, though it is still less extensively studied than DEET or picaridin.
Other Important Insect Repellent Measures
Clothing Protection
Wear light-colored clothing with long sleeves and long pants when possible.
Tuck pants into socks when hiking in wooded or grassy areas.
Perform tick checks after outdoor activity, especially around:
scalp
behind knees
groin
armpits
Permethrin-Treated Clothing
Clothing and gear can be treated with permethrin for added protection.
Popular brands: Sawyer
Updated Information
Permethrin is highly effective against ticks and mosquitoes.
It should be applied only to clothing and gear—not directly to skin.
Pre-treated clothing can remain effective through multiple wash cycles.
Benefits of Permethrin-Treated Clothing
Highly effective against ticks, mosquitoes, and biting flies
Provides stronger tick protection than many skin-only repellents
Remains effective through multiple washes depending on formulation
Especially useful for:
hiking
camping
gardening
hunting
outdoor sports
travel to wooded or grassy regions
Environmental Insect Repellent Measures
Avoid tall grass and dense brush when possible.
Stay on maintained or paved paths.
Eliminate standing water around the home:
flower pots
gutters
bird baths
buckets
kiddie pools
Newer Recommendations
Use window screens and repair tears promptly.
Outdoor fans on patios can reduce mosquito activity because mosquitoes are weak fliers.
Tick populations are expanding geographically in many parts of the U.S., including Ohio,
making prevention more important than ever.
Special Insect Repellent Considerations for Kids
Children can safely use insect repellent when products are chosen appropriately and applied
correctly. The best-supported options for children are:
Picaridin 10–20% — often preferred because it is less irritating, low odor, and does not damage clothing or plastics.
DEET 10–30% — considered safe for children older than 2 months when used as directed.
Oil of Lemon Eucalyptus (OLE/PMD) — should NOT be used in children under 3 years old.
Tips for Safe Use in Children
An adult should apply the repellent.
Avoid applying to:
hands
eyes
mouth
irritated or broken skin
Do not spray directly onto the face; spray onto hands first, then apply.
Wash treated skin with soap and water once indoors.
Combination sunscreen/repellent products are generally not recommended because sunscreen often needs more frequent reapplication than insect repellent.
For most families, picaridin-based repellents are increasingly becoming the preferred choice
for children because they provide long-lasting protection with less odor and skin irritation.
Sources:
Centers for Disease Control and Prevention insect repellent guidance
Environmental Protection Agency registered repellent recommendations
Nguyen QD, Vu MN, Hebert AA. Insect Repellents: An updated review for the clinician.
Q J Am Acad Dermatology. 2018;88:123-130.
Recent CDC and EPA guidance updates through 2025.












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